We can use “embryo surgery” called zona drilling or assisted hatching to “soften” the shell of the embryo. This helps to increase pregnancy rates by improving implantation rates, since embryo hatching is facilitated.
In the past, this was done using acid (acid Tyrode’s), but this can damage the embryo.
Today, we can precisely create an opening in the zona safely and effectively with the use of a laser.
Indications for Laser Assisted Hatching
Those patients who have IVF or ICSI who are over 37 years
Patients having Frozen Embryo transfer.
Patients who have had a previous failed IVF or ICSI treatment cycle
Patients undergoing IVF/ICSI for the first time, who are considered poor responders because they have required a high dose of gonadotrophins for poor ovarian response
Patients who in an earlier IVF cycle have had a low fertilization rate, for example, less than one-third of the embryos achieving fertilisation
Patients with three or less embryos
Patients who request laser assisted hatching and are fully informed of its use and function